Search results for "vector [correlation function]"
showing 10 items of 339 documents
Lie algebra on the transverse bundle of a decreasing family of foliations
2010
Abstract J. Lehmann-Lejeune in [J. Lehmann-Lejeune, Cohomologies sur le fibre transverse a un feuilletage, C.R.A.S. Paris 295 (1982), 495–498] defined on the transverse bundle V to a foliation on a manifold M, a zero-deformable structure J such that J 2 = 0 and for every pair of vector fields X , Y on M: [ J X , J Y ] − J [ J X , Y ] − J [ X , J Y ] + J 2 [ X , Y ] = 0 . For every open set Ω of V, J. Lehmann-Lejeune studied the Lie Algebra L J ( Ω ) of vector fields X defined on Ω such that the Lie derivative L ( X ) J is equal to zero i.e., for each vector field Y on Ω : [ X , J Y ] = J [ X , Y ] and showed that for every vector field X on Ω such that X ∈ K e r J , we can write X = ∑ [ Y ,…
No-Reference 3D Mesh Quality Assessment Based on Dihedral Angles Model and Support Vector Regression
2016
International audience; 3D meshes are subject to various visual distortions during their transmission and geometrical processing. Several works have tried to evaluate the visual quality using either full reference or reduced reference approaches. However, these approaches require the presence of the reference mesh which is not available in such practical situations. In this paper, the main contribution lies in the design of a computational method to automatically predict the perceived mesh quality without reference and without knowing beforehand the distortion type. Following the no-reference (NR) quality assessment principle, the proposed method focuses only on the distorted mesh. Specific…
FCA-Net: Adversarial Learning for Skin Lesion Segmentation Based on Multi-Scale Features and Factorized Channel Attention
2019
International audience; Skin lesion segmentation in dermoscopic images is still a challenge due to the low contrast and fuzzy boundaries of lesions. Moreover, lesions have high similarity with the healthy regions in terms of appearance. In this paper, we propose an accurate skin lesion segmentation model based on a modified conditional generative adversarial network (cGAN). We introduce a new block in the encoder of cGAN called factorized channel attention (FCA), which exploits both channel attention mechanism and residual 1-D kernel factorized convolution. The channel attention mechanism increases the discriminability between the lesion and non-lesion features by taking feature channel int…
The impacts of the ALE and hydrostatic-pressure approaches on the energy budget of unsteady free-surface flows
2008
Abstract This paper focuses on the energy budget in the calculation of unsteady free-surface flows on moving grids with and without using the ‘arbitrary Lagrangian–Eulerian’ (ALE) formulation or hydrostatic-pressure assumption. The numerical tool is an in-house general-purpose solver for the unsteady, incompressible and homogeneous Navier–Stokes equations in a Cartesian domain. An explicit fractional-step method and co-located finite-volume method are used for the second-order accurate integrations in time and space. The test cases are nonlinear and linear irrotational standing waves, which allow to characterise the impacts of an ALE or Eulerian formulation with moving grids by comparison w…
Extending the spectral decomposition of Granger causality to include instantaneous influences: application to the control mechanisms of heart rate va…
2021
Assessing Granger causality (GC) intended as the influence, in terms of reduction of variance of surprise, that a driver variable exerts on a given target, requires a suitable treatment of ‘instantaneous’ effects, i.e. influences due to interactions whose time scale is much faster than the time resolution of the measurements, due to unobserved confounders or insufficient sampling rate that cannot be increased because the mechanism of generation of the variable is inherently slow (e.g. the heartbeat). We exploit a recently proposed framework for the estimation of causal influences in the spectral domain and include instantaneous interactions in the modelling, thus obtaining (i) a novel index…
A Nullclines Approach to the Study of 2D Artificial Network
2019

 
 The system of two the first order ordinary differential equations arising in the gene regulatory networks theory is studied. The structure of attractors for this system is described for three important behavioral cases: activation, inhibition, mixed activation-inhibition. The geometrical approach combined with the vector field analysis allows treating the problem in full generality. A number of propositions are stated and the proof is geometrical, avoiding complex analytic. Although not all the possible cases are considered, the instructions are given what to do in any particular situation.
Non-small cell lung cancer (NSCLC), EGFR downstream pathway activation and TKI targeted therapies sensitivity: Effect of the plasma membrane-associat…
2017
Adenocarcinoma of Non-Small Cell Lung Cancer (NSCLC) is a severe disease. Patients carrying EGFR mutations may benefit from EGFR targeted therapies (e.g.: gefitinib). Recently, it has been shown that sialidase NEU3 directly interacts and regulates EGFR. In this work, we investigate the effect of sialidase NEU3 overexpression on EGFR pathways activation and EGFR targeted therapies sensitivity, in a series of lung cancer cell lines. NEU3 overexpression, forced after transfection, does not affect NSCLC cell viability. We demonstrate that NEU3 overexpression stimulates the ERK pathway but this activation is completely abolished by gefitinib treatment. The Akt pathway is also hyper-activated upo…
Rational Design of a Carrier Protein for the Production of Recombinant Toxic Peptides in Escherichia coli
2016
Commercial uses of bioactive peptides require low cost, effective methods for their production. We developed a new carrier protein for high yield production of recombinant peptides in Escherichia coli very well suited for the production of toxic peptides like antimicrobial peptides. GKY20, a short antimicrobial peptide derived from the C-terminus of human thrombin, was fused to the C-terminus of Onconase, a small ribonuclease (104 amino acids), which efficiently drove the peptide into inclusion bodies with very high expression levels (about 200-250 mg/L). After purification of the fusion protein by immobilized metal ion affinity chromatography, peptide was obtained by chemical cleavage in d…
Constant circulation sequences of binary neutron stars and their spin characterization
2018
For isentropic fluids, dynamical evolution of a binary system conserves the baryonic mass and circulation; therefore, sequences of constant rest mass and constant circulation are of particular importance. In this work, we present the extension of our Compact Object CALculator (\cocal{}) code to compute such quasiequilibria and compare them with the well-known corotating and irrotational sequences, the latter being the simplest, zero-circulation case. The circulation as a measure of the spin for a neutron star in a binary system has the advantage of being exactly calculable since it is a local quantity. To assess the different measures of spin, such as the angular velocity of the star, the q…
Jet launching from binary black hole-neutron star mergers: Dependence on black hole spin, binary mass ratio and magnetic field orientation
2018
Black hole-neutron star (BHNS) mergers are one of the most promising targets for multimessenger astronomy. Using general relativistic magnetohydrodynamic simulations of BHNS undergoing merger we showed that a magnetically--driven jet can be launched by the remnant if the NS is endowed with a dipole B field extending from the interior into the exterior as in a radio pulsar. These self-consistent studies considered a BHNS system with mass ratio $q=3:1$, BH spin $a/M_{BH}=0.75$ aligned with the total orbital angular momentum (OAM), and a NS that is irrotational, threaded by an aligned B field, and modeled by an $\Gamma$--law equation of state with $\Gamma=2$. Here, as a crucial step in establi…